I can't see any reason why this needs Python2, especially since the Python 
scripts in PLIST are commented out.

ok?

Index: Makefile
===================================================================
RCS file: /cvs/ports/devel/arm-none-eabi/gdb/Makefile,v
diff -u -p -u -r1.14 Makefile
--- Makefile	3 Dec 2024 01:12:22 -0000	1.14
+++ Makefile	24 May 2025 19:35:54 -0000
@@ -2,7 +2,7 @@ COMMENT=	gdb for arm-none-eabi cross-dev
 
 DISTNAME=	gdb-7.12.1
 EXTRACT_SUFX=	.tar.xz
-REVISION=	0
+REVISION=	2
 
 HOMEPAGE=	https://www.gnu.org/software/gdb/
 
@@ -24,7 +24,6 @@ CONFIGURE_ARGS+=	--enable-multilib \
 			--without-guile
 
 MODULES=	lang/python
-MODPY_VERSION =	${MODPY_DEFAULT_VERSION_2}
 
 TEST_DEPENDS=devel/dejagnu